Birmingham adult centre
This centre leads in developing personalised cancer therapies in partnership with University Hospitals Birmingham and Cancer Research UK’s Clinical Trials Unit at the University of Birmingham.
Centre overview
Our Birmingham adult experimental cancer medicine centre (ECMC) delivers research at the University Hospitals Birmingham, one of England’s largest teaching trusts.
As part of the network, the Birmingham ECMC also launched the Tessa Jowell Brain Matrix and the National Lung Matrix Trial, the largest precision medicine study in non-small cell lung cancer globally at the time.
There is also a paediatric centre in Birmingham.
Expertise
precision medicine
biomarker research
immunotherapy
cellular therapies
cancer genomics
cancer metabolism
Patient population
Between 2024-2025
10,520
10,520 new cancer cases within the NHS trust
15%
15% were recruited onto cancer trials
Key contacts

Gary Middleton - Centre lead
Gary Middleton, Chair of Medical Oncology at Birmingham since 2013, is Clinical Director for the Cancer Research UK Birmingham Centre and leads their Clinical Academic Training Programme. He specialises in lung and colorectal cancer. His focus is on stratified patient treatment and novel trial design, serving as Chief Investigator for the National Lung Matrix Trial.
Fayeon Fyfield-Calder - Centre business lead
Fayeon Fyfield-Calder oversees the operational delivery of the Birmingham ECMC. She manages the centre’s day-to-day operations, supports ECMC-funded staff, facilitates access to cutting-edge research studies and advances key experimental cancer initiatives.

Karen Turner - Patient and public involvement lead
Karen Turner is a Cancer Research UK Senior Research Nurse based at the University of Birmingham. With over 34 years of cancer nursing experience, 27 years of which have been in early phase cancer clinical research nursing. Karen is passionate about incorporating the lived experience of patients and their families within the research process.
Contact details
Cancer Research UK Clinical Trials Unit
Department of Cancer and Genomic Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
Centre email:
Programme office email:
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