Liverpool adult centre
This centre is a collaboration between University of Liverpool and Clatterbridge Cancer Centre NHS Foundation Trust, advancing biomarker discovery, personalised medicine, trial design and delivery.
Centre overview
Our Liverpool adult experimental cancer medicine centre (ECMC) delivers trials and translational research in key areas of clinical expertise, including hepato-pancreato-biliary, head and neck and thoracic cancers.
Their focus is on developing and validating predictive and therapeutic biomarkers (including immune biomarkers), designing and delivering biomarker-stratified and personalised vaccine trials, developing novel statistical methodologies and translational research into tumour microenvironment and immune cell biology.
Working with the NIHR Liverpool Clinical Research Facility, the centre delivers complex trials involving radiopharmaceuticals, nuclear medicine and complex pharmacokinetic schedules. Their research is underpinned by a Good Clinical Practice laboratory facility.
There is also a paediatric centre in Liverpool.
Expertise
Hepato-pancreato-biliary cancers
head and neck cancers
haemato-oncology
biomarker validation
immunophenotyping
novel statistical methodology
next generation deep sequencing
spatial transcriptomics
Patient population
Between 2024-2025
14,196
14,196 new cancer cases within the NHS trust
1,170
1,170 recruited onto clinical trials
Key contacts

Daniel Palmer - Centre co-lead
Daniel Palmer is the North West Cancer Research Chair in Medical Oncology at the University of Liverpool. He focuses on hepato-pancreato-biliary (HPB) cancers, developing early-phase trials and translational studies which investigate immune-based therapies, target the tumour microenvironment and develop biomarker-driven approaches for HPB cancer.

Bill Greenhalf - Centre co-lead
Bill Greenhalf is Professor of Molecular Oncology at the University of Liverpool and Director of the Good Clinical Practice Laboratory facility. His research focuses on pancreatic cancer genetics, early detection and translational trials. He holds lead roles in the Liverpool ECMC and the European Registry of Hereditary Pancreatic Diseases, with extensive academic and industry experience.

Charlotte Rawcliffe - Centre business co-lead
Charlotte is the Liverpool ECMC operational director. She is an experienced clinical research professional with more than 20 years of expertise in the design, management and delivery of complex clinical trials. She has extensive experience overseeing international multi-centre oncology trials and has played a key role in trial methodology development and process optimisation.

Sara Martin - Centre business co-lead
Sara Martin has over 15 years of experience working within oncology research in both the NHS and academic settings. Sara has managed the set-up and delivery of a wide range of research studies, including an international registry, screening studies, biobanking initiatives and phase 1-2 clinical trials.

Carlo Palmieri - Patient and public involvement lead
Carlo Palmieri is a Professor of Translational Oncology and a Consultant Medical Oncologist. He focuses on endocrine breast cancer therapy and leads a portfolio of translational studies and clinical trials in metastatic breast cancer. Carlo has extensive experience in patient and public involvement and engagement, including co-production of research outputs and leading participant-facing events.
Contact details
ECMC Office, Office 294
William Henry Duncan Building
6 West Derby Street
University of Liverpool
Liverpool
L7 8TX
Centre email:
liverpool-ecmc@liverpool.ac.uk
Programme office email:
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